Abstract

Pseudoprogression denotes apparent, early progression of disease followed by long-lasting regression. This phenomenon is observed during the treatment of different cancers and in approximately 10% of patients receiving immunotherapy. The appearance of pseudoprogression could make difficult the assessment of treatment response based on Response Evaluation Criteria in Solid Tumours (RECIST). In this report, the scope of pseudoprogression was discussed as well as currently proposed alternative methods of treatment response assessment according to Immune-related Response Criteria (irRC).

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