Pseudoangiomatous stromal hyperplasia \u2013 a benign and rare tumor of the breast in an adolescent: a case report

Alberto Testori,Stefano Meroni,Marco Alloisio,Bethania Fernandez,Valentina Errico,Edoardo Bottoni,Emanuele Voulaz,Ugo Cioffi,Matilde De Simone

doi:10.1186/s13256-017-1426-9

Abstract

BackgroundPseudoangiomatous stromal hyperplasia is an uncommon mesenchymal breast neoplasm.Case presentationHere we present a case of an 11-year old hispanic girl affected by bilateral mammary nodular pseudoangiomatous stromal hyperplasia, an uncommon breast disease, with a review of the literature related to diagnostic workup, differential diagnosis, and management. A rapidly growing mass in the breast may be stressful for both parents and child as the suspicion of malignancy arises. Multiple wide excisions of both breasts were performed.ConclusionsThe purpose of this case report is to draw attention to the fact that most emerging lesions of the breast in girls during puberty are benign diseases.

Highlights

Pseudoangiomatous stromal hyperplasia is an uncommon mesenchymal breast neoplasm
We report a rare case of an adolescent girl who presented with a bilateral breast Pseudoangiomatous stromal hyperplasia (PASH) that occurred just after menarche and showed rapid growth over a short time period
Its prevalence is difficult to accurately estimate, tumor-forming PASH is an uncommon mesenchymal neoplasm of the breast and typically affects women in the reproductive age group; it is extremely rare in an adolescent girl, such as in our case report

Summary

Background

Breast masses are uncommon in children and adolescents. The majority of them are benign tumors like fibroadenomas [1,2,3] or are associated with inflammation due to infection. We report a rare case of an adolescent girl who presented with a bilateral breast PASH that occurred just after menarche and showed rapid growth over a short time period. This case is a diagnostic and therapeutic challenge, taking into account our patient’s age and the controversial treatment recommendations. Taking into account our patient’s age, clinical presentation, and tumor size, a multidisciplinary team recommended multiple wide surgical excisions not to be followed by adjuvant therapy Wide excisions of her breasts were performed for complete removal of the Testori et al Journal of Medical Case Reports (2017) 11:284.

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