HAMARTOMA E HIPERPLASIA ESTROMAL PSEUDOANGIOMATOSA DE LA MAMA, DIAGNÓSTICOS DIFERENCIALES INFRECUENTES DE CÁNCER DE MAMA: Differential diagnosis

Abstract

Hamartoma and nodular pseudoangiomatous stromal hyperplasia. Differential diagnosis Introduction: Hamartoma and nodular pseudoangiomatous stromal hyperplasia (PASH) are inusual breast tumor entities, however, can simulate breast cancer. The only accurate tool is preoperative biopsy. Sur- gical treatment is curative with low recurrence rate. Objective: To present a case of mammary hamartoma as- sociated with PASH whose initial presentation was suggestive of probable malignancy. Case Report: Woman, 44 years old, admitted to controls because of probable malignant breast disease, mammography was reported as BIRADS 0, breast ultrasound as BIRADS U.S: 5, CORE biopsy reported PASH. Partial mastectomy was performed. On delayed biopsy mammary hamartoma with extensive stromal hyperplasia pseudoangiomatosa was diagnosed. Discussion: PASH and hamartomas are diseases with no specific clinical presentation, radiolo - gical findings may be pathognomonic of hamartoma, while not in PASH. In the reported case the pathological study showed an association of these conditions, described in a 16% to 71% breast hamartoma cases. The analysis of the entire surgical specimen is essential for a definitive diagnosis.