Abstract

Pioglitazone is a PPAR- agonist that redirects lipids from ectopic sites into subcutaneous adipose tissue and is hypothesized to improve mitochondrial function in skeletal muscle. This study assessed whether the insulin-sensitizing effect of pioglitazone is accompanied by improved skeletal muscle mitochondrial function and intramyocellular lipid (IMCL) levels in Zucker diabetic fatty rats using 31P and 1H magnetic resonance spectroscopy (MRS).

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.