Abstract

In this review, we discuss considerations and successful models for providing decentralized diagnosis, treatment, and prevention services for children and adolescents. Key approaches to building decentralized capacity for childhood TB diagnosis in primary care facilities include provider training and increased access to child-focused diagnostic tools and techniques. Treatment of TB disease should be managed close to where patients live; pediatric formulations of both first- and second-line drugs should be widely available; and any hospitalization should be for as brief a period as medically indicated. TB preventive treatment for child and adolescent contacts must be greatly expanded, which will require home visits to identify contacts, building capacity to rule out TB, and adoption of shorter preventive regimens. Decentralization of TB services should involve the private sector, with collaborations outside the TB program in order to reach children and adolescents where they first enter the health care system. The impact of decentralization will be maximized if programs are family-centered and designed around responding to the needs of children and adolescents affected by TB, as well as their families.

Highlights

  • One out of every six people who develop TB every year is a child or adolescent under 20 years old [1,2]

  • The COVID-19 pandemic has resulted in challenges to accessing TB services that have compounded this problem, resulting in a 24% decrease in notifications in the 0–14 age group and an 11% reduction in child contacts receiving TB preventive treatment (TPT) in 2020 compared to 2019 [1]

  • We review considerations and successful models for providing decentralized diagnosis, treatment, and prevention services for children and adolescents

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Summary

Introduction

One out of every six people who develop TB every year is a child or adolescent under 20 years old [1,2]. Children and adolescents affected by TB require access to radiography, gastric lavage, pediatric TB specialists, and youth-friendly clinics. These services are often concentrated in referral-level hospitals or specialized facilities. Children and adolescents generally access the health system through outpatient or maternal-child health clinics at primary care facilities or private general practitioners [4]. This mismatch between the location of services and the location of care-seeking leads to losses from care and delays in TB diagnosis, treatment, and prevention. We review considerations and successful models for providing decentralized diagnosis, treatment, and prevention services for children and adolescents

Decentralizing Diagnostic Services
Decentralizing Treatment of TB Disease
Decentralizing Preventive Services for Child and Adolescent Contacts
Engaging the Private Sector
Integrating TB Care with Other Services for Children and Adolescents
Recommendations
Findings
Conclusions
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