Abstract
Abdominal pain in systemic lupus erythematosus (SLE) is a common symptom. Forty percent of patients will present with abdominal pain during the course of the disease, although it may also be an initial manifestation of undiagnosed disease. The origin of the pain is diverse, as it can be similar to that of the general population or be the result of activity specific to SLE or a concomitant disease. As part of the initial approach, the need for urgent surgery should be ruled out; otherwise, a complete work-up should be undertaken, including clinical history taking with physical examination, laboratory tests, phase reactants and SLE activity parameters, and imaging on suspicion. A high index of suspicion should be kept for infection and neoplasia, and immunosuppressive treatment instituted once these possibilities have been discounted.
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