Abstract

Hyperprolactinemia is a common cause for assessment in clinical endocrinology practice. It can have several causes, including prolactinoma, the most common functioning pituitary tumor. In order to reach an accurate differential diagnosis, it is essential to take a detailed medical history to rule out possible physiological or pathological causes. Non-tumoral hyperprolactinemia of pathological origin is usually associated with pharmacological factors as the predominant cause. Typical clinical symptoms include galactorrhea and manifestations resulting from hypogonadism induced by excess prolactin. The clinical presentation may vary according to gender, age, and underlying cause. The necessary additional tests, including magnetic resonance imaging, should be performed based on the medical history.

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