Abstract
Pyrosis is one of the typical symptoms of gastroesophageal reflux disease. It is one of the most common causes for consultation in primary care and gastrointestinal department clinical practice. In Spain, it has been reported that approximately one out of every three people has pyrosis on a regular basis. Therefore, its diagnosis is of utmost importance. Pyrosis’ favorable response to empirical treatment with proton pump inhibitors allows for diagnosing it in the absence of alarm symptoms. If alarm signs are present, an upper gastrointestinal endoscopy (UGIE) should be performed as soon as possible. Patients who do not respond to medical treatment and whose UGIE does not show abnormalities compatible with gastroesophageal reflux disease should undergo a pH meter test±esophageal impedance testing without treatment.
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