Abstract
Hormone replacement therapy (HRT) is a treatment for postmenopausal women to improve quality of life and the adverse effects associated with hormonal deficiencies that occur at this stage of life. In most healthy women under 60 years of age who are in early menopause (within the first 10 years of the onset of menopause), the benefits of HRT outweigh the risks. Initiation of HRT in the 60-70 age group requires an individualized risk/benefit calculation, consideration of other available drugs, and the lowest effective dose. HRT should generally not be started after age 70. Estrogen formulations are the most effective therapeutic option available and the addition of progesterone is intended to protect against the consequences of systemic estrogen therapy in women with intact uteruses.
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