Proteomics Loans in Kinetoplastids during the Last Decade

Abstract

Kinetoplastida are flagellated protists characterized by the presence of an organelle called kinetoplast. This characteristic feature is an unusual large DNA- containing granule located within the single mitochondrion, associated with the basal body of the cell’s flagellum. It contains many copies of the mitochondrial genome. These organisms are commonly referred to as “kinetoplastids”. This group comprises parasites responsible for serious diseases in humans as well as other animals. Among kinetoplastids, the family of Trypanosomatids, is notable as it includes some organisms which are exclusively parasitic such as Trypanosoma and Leishmania.