Abstract

Proteinuria in HIV Positive Children in Port Harcourt, Nigeria

Highlights

  • Infection with Human Immunodeficiency Virus (HIV) is of public health concern worldwide but more in sub-Saharan Africa, home to 71% of the world’s HIV infected people [1,2]

  • There was no positive correlation between proteinuria and the clinical stage of HIV infection in the subjects

  • The prevalence of proteinuria using dipstick urinalysis is low in HIV positive children seen in University of Port Harcourt Teaching Hospital (UPTH) Port Harcourt

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Summary

Introduction

Infection with Human Immunodeficiency Virus (HIV) is of public health concern worldwide but more in sub-Saharan Africa, home to 71% of the world’s HIV infected people [1,2]. HIV which causes acquired immunodeficiency syndrome (AIDS) [1], is a major cause of infant and childhood morbidity and mortality in Africa and the rest of the world [3,4]. Of the two types of HIV that infect humans-HIV-1 and HIV2, HIV-1 is more virulent, more transmissible and the cause of the vast majority of HIV infections globally [9]. The virus affects virtually every system in the body including the kidneys with a resultant variety of renal abnormalities that culminate in HIVAN [10,11]. HIV-associated nephropathy (HIVAN) is a common complication of HIV infection and significant proteinuria is associated with HIVAN

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