Abstract
Cell suspensions of the Yoshida ascites hepatoma were irradiated in air with increasing x-ray doses (10 to 100 kr). Aerobic and anaerobic glycolysis, oxygen uptake, and incorporation of C/sup 14/-leucine into protein were measured immediately thereafter. Definite inhibitions of both the glycolysis and the glycolysis-related incorporation were observed. The oxygen uptake as well as the incorporation related to the oxidative metabolism remained unimpaired. Evidence was presented that a linear reduction of glycolysis is paralleled by an exponential reduction of amino acid incorporation. Although the aerobic glycolysis was markedly depressed by x rays, the Crabtree effect was not reversed. (auth)
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