Protein ADP-Ribosylation Takes Control in Plant-Bacterium Interactions.

Baomin Feng,Libo Shan,Chenglong Liu,Ping He,Cyril Zipfel

doi:10.1371/journal.ppat.1005941

Abstract

Protein ADP-Ribosylation Takes Control in Plant-Bacterium Interactions.

Highlights

Sessile plants detect and ward off invading microorganisms with a robust and sophisticated innate immune system in addition to structural, physical, and chemical barriers [1]
The first line of the plant immune system depends on pattern-recognition receptors (PRRs) that recognize conserved pathogen- or microbe-associated molecular patterns (PAMPs or MAMPs) and induce pattern-triggered immunity (PTI) [2]
Protein ADP-ribosylation as a versatile molecular switch has been utilized by plants as an intrinsic regulatory mechanism for immunity and by bacteria as an effective invasion strategy for pathogenicity

Summary

Introduction

Sessile plants detect and ward off invading microorganisms with a robust and sophisticated innate immune system in addition to structural, physical, and chemical barriers [1]. Recent studies show that protein ADP-ribosylation, an important yet less studied posttranslational modification with an emerging role in diverse cellular processes, is exploited both by plants to launch effective defense and by bacteria to achieve stealthy attacks to the hosts. We summarize the classification and biochemical processes of protein ADP-ribosylation, compare the similarities and differences of ADP-ribosylation in plants and animals, and discuss the roles of ADP-ribosylation in plant immunity and bacterial pathogenicity.

Results

Conclusion