Abstract
20Feb 2019 PROTECTIVE ROLE OF VITAMIN C ON HISTOPATHOLOGICAL EFFECT OF FORMALDEHYDE ON REPRODUCTIVE SYSTEM IN FEMALE ALBINO MICE (HISTOLOGICAL STUDY). Soad A. Treesh , Suhera M. Aburawi , Medeha T. Elghedamsi , Habiba A. El Jaafari , Rima Alzowam , Naema Shibani and Nadia S. Khair. Department of Histology and Medical Genetics, Faculty of Medicine, University of Tripoli, LIBYA. Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, University of Tripoli, LIBYA. Zoology Department, Science Faculty - University of Tripoli, LIBYA. Department of Histology, Faculty of Medicine, Menoufia University, Egypt.
Highlights
Infertility refers to the biological inability of an individual to contribute to conception, or to a female who cannot carry a pregnancy to full term
On the sixth day female mice were divided into 5 groups: group 1 administered normal saline (5 ml/kg) for 5 days, group 2 received formaldehyde (30 mg/kg) for 5 days, group 3 received vitamin C (250mg/kg) for 5 days, group 4 administered formaldehyde and vitamin C for 5 days, group 5 received formaldehyde for 5 days followed by vitamin C for another 5 days
Vitamin C (Prophylaxis) exposure ovaries: The ovaries of this group showed the presence of growing follicles but very little of primordial follicle, proliferation of the interstitial cells among growing follicles, tunica albuginea covering the ovary thicker than the control group, numerous dilated blood vessels in interstitial tissue among atretic follicles & corpora lutea were observed (Fig.5 a,b)
Summary
Infertility refers to the biological inability of an individual to contribute to conception, or to a female who cannot carry a pregnancy to full term.
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