Abstract
Abstract The toxicity by inhalation of combustion and pyroiysis products of a PVC and a wood (Douglas Fir) has been studied by the physiogram method, in the rabbit in controlled ventilation and by the mask cage method in spontaneous ventilation. The protecting effect of water was evaluated by trapping the gases and vapors with an impinger placed on the air flow just before the animals. Combustion and pyrolysis products were generated by an annular furnace moving along a strip of samples. The temperature of the furnace was 400°C for smoldering conditions and 850°C for flaming conditions. CO, CO2, 02, and HC1 were determined in the atmospheres; pO2, pCO2, pH, CO, COHb in the animals' blood and EEG, EKG, and arterial pressure were recorded. The animals are very significantly protected by water against PVC fumes (HC1 is very soluble in water) and in part protected against fumes from combustion of wood. In both cases, CO is not trapped and seems to be then the determinant toxicant.
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