Abstract

BackgroundDespite growing interest in use of lipid nutrient supplements for preventing child malnutrition and morbidity, there is inconclusive evidence on the effectiveness, and no evidence on the cost-effectiveness of this strategy.MethodsA cost effectiveness analysis was conducted comparing costs and outcomes of two arms of a cluster randomized controlled trial implemented in eastern Chad during the 2010 hunger gap by Action contre la Faim France and Ghent University. This trial assessed the effect on child malnutrition and morbidity of a 5-month general distribution of staple rations, or staple rations plus a ready-to-use supplementary food (RUSF). RUSF was distributed to households with a child aged 6–36 months who was not acutely malnourished (weight-for-height > = 80% of the NCHS reference median, and absence of bilateral pitting edema), to prevent acute malnutrition in these children. While the addition of RUSF to a staple ration did not result in significant reduction in wasting rates, cost-effectiveness was assessed using successful secondary outcomes of cases of diarrhea and anemia (hemoglobin <110 g/L) averted among children receiving RUSF.Total costs of the program and incremental costs of RUSF and related management and logistics were estimated using accounting records and key informant interviews, and include costs to institutions and communities. An activity-based costing methodology was applied and incremental costs were calculated per episode of diarrhea and case of anemia averted.ResultsAdding RUSF to a general food distribution increased total costs by 23%, resulting in an additional cost per child of 374 EUR, and an incremental cost per episode of diarrhea averted of 1,083 EUR and per case of anemia averted of 3,627 EUR.ConclusionsAdding RUSF to a staple ration was less cost-effective than other standard intervention options for averting diarrhea and anemia. This strategy holds potential to address a broad array of health and nutrition outcomes in emergency settings where infrastructure is weak and other intervention options are infeasible in the short-term. However, further research is needed to establish the contexts in which RUSF is most effective and cost-effective in preventing acute malnutrition and morbidity among vulnerable children, compared to other options.

Highlights

  • Despite growing interest in use of lipid nutrient supplements for preventing child malnutrition and morbidity, there is inconclusive evidence on the effectiveness, and no evidence on the cost-effectiveness of this strategy

  • Several studies have assessed the effect on these outcomes of Lipid Nutrient Supplements (LNS) in both supplementary and therapeutic form, i.e. ready-to-use supplementary foods (RUSF) and ready-to-use therapeutic foods (RUTF)

  • While the present analysis provides more comprehensive cost estimates, and takes place in an emergency setting with high logistics costs, it is likely that given the equal or greater effect of sprinkles on hemoglobin concentration and anemia prevalence [57], that the cost-effectiveness of sprinkles would be greater than that of LNS in averting cases of anemia

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Summary

Introduction

Despite growing interest in use of lipid nutrient supplements for preventing child malnutrition and morbidity, there is inconclusive evidence on the effectiveness, and no evidence on the cost-effectiveness of this strategy. Use of therapeutic food products, in the form of Lipid Nutrient Supplements (LNS), has been well-documented as a proven method to treat severe acute malnutrition (wasting) in children [1,2,3]. There has been growing interest in the potential of LNS for preventive benefits on child nutrition and health outcomes when used as a complementary food or a micronutrient-rich food supplement for young children, in the context of humanitarian emergencies [4]. Evidence is inconclusive on the effectiveness of fortified foods (including LNS) in preventing deterioration of child health and nutrition status. Other research has shown equivocal evidence of the superiority of LNS to CSB in prevention [11] and treatment [12,13,14] of moderate wasting

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