Abstract

Adenocarcinoma of prostate typically involves axial skeleton and has been infrequently reported in unusual sites like orbit. It is noteworthy that upto 1989, only 28 cases of occulo-orbital metastases of prostate cancer (PC) had been reported in the literature [1] . PC is mostly known to metastasize to the bony skeleton [2] . The lack of skeletal metastasis does not exclude the possibility of visceral/ distant metastasis, and serum PSA levels usually do not correlate with the extent of metastatic disease [3] . Here in, we report a rare case of unilateral orbital metastasis from PC.

Highlights

  • Among adults, orbital metastases are most commonly of epithelial origin and it would seem that orbital metastases are site specific, being not just a part of bony metastases [4]-[9]

  • prostate cancer (PC) accounts for only 3.6% of orbital metastases encountered in clinical practice

  • Serum PSA levels usually do not correlate with the extent of metastatic disease.[3]

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Summary

1.Introduction

Orbital metastases are most commonly of epithelial origin and it would seem that orbital metastases are site specific, being not just a part of bony metastases [4]-[9]. Several epithelial tumours have been documented to show orbital metastases, including oesophageal[10], breast[11], pancreatic[12] and lung[13] cancers. Metastatic carcinoma to the orbit constitutes only between 2.3% and 7% of all orbital tumours[14][15]. They are predominantly Bilateral, rarely unilateral orbital metastases are reported. It is noteworthy that upto 1989, only 28 cases of occulo-orbital metastases of prostate cancer (PC) had been reported in the literature.[1]. When PC presents with metastasis in the orbit, it is usually a late event and often the patient is in the terminal stages of the disease [6][7]. We are reporting a case of unilateral Orbital secondary from primary PC

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