Abstract
Objectives: to describe the characteristics of newly diagnosed prostate cancer (PCa) and the initial treatments offered to patients in the most important urological center of Burkina Faso. Methods: We analyzed the data of a cohort of 168 consecutive patients with no prior history of PCa between January 2009 and December 2012. Diagnosis of PCa was based on histological analysis of transrectal prostate biopsies. Patient and disease characteristics and the initial treatment offered were taken in account. Results: The mean age at presentation was 68.59 ± 9.41 years (range 30 to 95 years). There was a 3.6-fold increase in the incidence of PCa through the four years of the study. The mean duration of symptoms prior to presentation was 11.6 ± 10.9 months. The majority of cases (86.9%) were presented as locally advanced or metastatic disease. Androgen deprivation therapy (ADT) was the first therapeutic option for 121 patients (72%) and 73 patients (43.4%) underwent ADT through bilateral orchiectomy. Only 3 patients (1.78%) underwent radical prostatectomy. Conclusion: An increase in the diagnosis of PCa in our country was observed in this study. The diagnosis of prostate cancer was usually tardive in Burkina Faso. Treatment often involves surgical ADT for socioeconomic reasons.
Highlights
Prostate cancer (PCa) is the second most common cause of cancer and the sixth leading cause of cancer death among men worldwide with an estimated 899,000 new cases and 258,000 new deaths in 2008 [1]
The aim of the present study is to provide more data concerning characteristics of newly diagnosed PCa and an overview of initial treatments offered in the
Diagnosed PCa cases were included between January 2009 and December 2012 at the urology division of the Yalgado Ouedraogo University Teaching Hospital of Ouagadougou. 168 consecutives cases were enrolled during the study period and their details entered into a database
Summary
Prostate cancer (PCa) is the second most common cause of cancer and the sixth leading cause of cancer death among men worldwide with an estimated 899,000 new cases and 258,000 new deaths in 2008 [1]. The International Agency for Research on Cancer (IARC) estimates that PCa is a growing problem in Africa: approximately 57.048 African men will die of PCa in the two decades [1,2]. Despite this dramatically increase of the dis-. Ease impact, PCa cases remain under diagnosed and underreported in Sub-Saharan Africa (SSA). Previous studies in Burkina Faso are suggestive that PCa knowledge and awareness are pour in the general population [4] and that most cases are diagnosed late [5].
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