Prospective observational study on prescription pattern of antibiotics in general ward and intensive care unit in tertiary care hospital

Abstract

The prescription pattern monitoring facilitate the rational use of drugs in the population. Rational use of drug means patients receive medication appropriate to their clinical needs in closes that meet the individual requirement for an adequate period of time and at an economical price to the individual and overall to the community. Role of Right medicine in the Right manner in the Right patients must be followed while using Antibiotics. Irrational use of medicines is major problem worldwide. WHO estimates that more than half of all medicines are prescribed, dispensed or sold inappropriately and that half of all patients fail to take them correctly. The overuse, underuse or misuse of medicine result in wastage of scarce resource and widespread health hazards. Therefore, appropriate and safe use of antibiotics in healthcare system is more Important. The main objective of the study was to determine the percentage of antibiotics used in general ward and in intensive care unit and to find out most commonly Prescribed antibiotic within 72 hours in intensive care unit, the most common microorganism found in culture sensitivity test and the common route of drug administration in general ward and in intensive care unit. This is a prospective observational study. The study was conducted in tertiary care hospital in Gujarat. The duration of the study was 6 months. Total of 120 patients data was collected from the patient case sheet. Prescription of the patients are collected in designed CRF form and relevant data is analysed to obtain frequency and percentage. Out of 120 patients, majority of patients were male and most commonly used route of administered was Iv. The commonly prescribed antibiotics in general ward was ceftriaxone 28 (29.43%), metronidazole 10 (10.53%), cefoperazone + sulbactum 10 (10.53 %) and Amoxicilin + clavulanic acid 7 (7.37 %) prescribed for different condition. In Intensive care unit, commonly prescribed antibiotics was ceftriaxone 19 (18.1 %), meropenem 15 (14.29 %) and Cefoperazone + sulbactum 12 (11. 44 %). On Discharge Time most of the patients was still on antibiotics therapy.This study analysed 120 prescription and ceftriaxone, cefoperazone + sulbactum, amoxicillin + clavulanic acid, meropenem, cefadroxil ,vancomycin,cefepime + tazobactum piperacilin + tazobactum, doxycycline Cefixime are the hospital formulary. Prescription pattern studies have become a potential tool for evaluating the health care System. This study provides important baseline information on antibiotics use. This study severs to spotlight the current prescribing trends in patients. The use of a single agent and the combination of antibiotics were dependent upon the hospital formulary and protocols and policies for antibiotic use.