Abstract
Background Rarely, patients with normally sized RV and LV will undergo total cavopulmonary connection (TCPC) due to the complexity of their intracardiac anatomy giving them a dual ventricle (DV) for a single cardiac output. The ventricular function in this unique physiology compared to SRV, SLV and normal hearts remains poorly understood, with few studies performed. In this study, we perform a comprehensive comparison of global and regional strain in both the circumferential (ecc) and longitudinal (eL) dimensions to conventional SV hearts and normal hearts.
Highlights
Patients with normally sized RV and LV will undergo total cavopulmonary connection (TCPC) due to the complexity of their intracardiac anatomy giving them a dual ventricle (DV) for a single cardiac output
1.) Compared to normals, there is a significant reduction in global εcc at all ventricular levels of DV patients
2.) Compared to normals, there is a significant reduction in global εL in mid-ventricular and apical locations of DV patients
Summary
Patients with normally sized RV and LV will undergo total cavopulmonary connection (TCPC) due to the complexity of their intracardiac anatomy giving them a dual ventricle (DV) for a single cardiac output. The ventricular function in this unique physiology compared to SRV, SLV and normal hearts remains poorly understood, with few studies performed. We perform a comprehensive comparison of global and regional strain in both the circumferential (εcc) and longitudinal (εL) dimensions to conventional SV hearts and normal hearts. Purpose In normal subjects and asymptomatic patients with DV (LV and RV calculated independently), SLV and SRV after TCPC, to compare: 1) Global εcc and εL strain, 2) Regional circumferential and longitudinal strains at free wall (εcc-free, εL-free) and septum (εcc-sept, εL-sept), 3) εcc and εL across the ventricle from apex to base
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