PROSPECTIVE DIRECTIONS OF THE DEVELOPMENT OF BIOACTIVE GLASS FIBERS FOR MEDICAL APPLICATION

Abstract

The urgency of the development and use of glass fibers for the creation of microfiber dressings for the treatment of chronic wounds in combat conditions has been determined. The availability of such materials is especially important in the conditions of hostilities, which are characterized by the need for quick resuscitation of the wounded and the provision of emergency aid on the battlefield. The use of such materials will save life, shorten the rehabilitation period, and speed up the recovery of the military and civilian population. An analysis of the scientific and technical literature on the composition and properties of bioactive glass fibers for medical use was carried out. The compositions and properties of glass fibers for various purposes were analyzed and their possibility of use in the development of bioactive glass fibers for medical use was established. The selection of the compositions of bioactive glass fibers with a prolonged biocidal effect for the rapid healing of wounds and the restoration of bone tissue is substantiated. The mechanism of action of biocidal components and boron ions in the composition of bioglasses on the ability to inhibit the negative effects of pathogenic microorganisms was analyzed. The use of boroaluminophosphate glass fibers for the manufacture of effective dressings for the treatment of wounds in crisis situations in combat conditions will increase the percentage of survival and reduce the duration of treatment due to the direct action of cations and anions of the materials in vivo. The main theoretical principles of the creation of bioactive boroaluminophosphate glass fibers, modified with group II metal cations, which will be characterized by the presence of a strengthened surface layer, and characterized at the same time by high biocompatibility, biocide with prolonged action and non-toxicity, have been determined. The introduction of domestically developed bioactive glass fibers into medical practice will significantly increase the competitiveness of domestic medical materials, as well as ensure defense capability and safety, and contribute to the stabilization of the market in the conditions of sustainable development of the state.