Abstract

Prostate cancer is the most common cancer in men after lung cancer. Generally, the segmentation of the prostate is the preprocessing work for the diagnosis of prostate cancer. Aiming at the variety of prostate and the similarity of visual characteristics between prostates and their surroundings, this paper proposes a new prostate segmentation network based on MR images, denoted as ProSegNet. ProSegNet consists of two parts: encoder and decoder. To improve the feature extraction capability of the encoder, we use dense blocks as the feature extraction unit, and at the same time introduce a cross-stage partial (CSP) structure to reduce the amount of calculation. In the design of the decoder structure, we integrated the spatial attention mechanism and the channel attention mechanism to enable it to focus on the important features while ignoring the invalid features. In addition, to segment the prostate more accurately, we add a prostate contour segmentation branch to the output of the segmentation network to learn the contour features of the prostate. Finally, to alleviate the problem of small intensity difference between the prostate and surrounding tissues, we designed a truncated intensity stretching image enhancement method. The performance of ProSegNet has been experimentally verified in the Promise12 and ProstateX datasets. On the Promise12 dataset, the dice similarity coefficient (DSC) and hausdorff (Haus) distance are 0.908 and 9.87 respectively. On the ProstateX dataset, the DSC and Haus reach the results of 0.892 and 10.45, respectively. Experimental results show that the ProSegNet can obtain a competitive performance.

Highlights

  • The prostate is the largest substantial organ in the accessory glands of the male genitalia, which has the physiological function of secreting and storing prostate fluid

  • This paper proposes a new method of prostate segmentation based on magnetic resonance (MR) images, denoted as ProSegNet

  • ProSegNet can automatically segment the prostate from the MR image and accurately determine the position, boundary, and volume of the prostate, so as to help clinicians quickly locate the prostate, identify abnormal shapes, and calculate the prostate specific antigen (PSA) concentration based on the volume

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Summary

INTRODUCTION

The prostate is the largest substantial organ in the accessory glands of the male genitalia, which has the physiological function of secreting and storing prostate fluid It is located at the bottom of the pelvic cavity, with a bladder on the top, a pubic bone in the front, and a rectum in the back [1]. Common diagnostic methods for prostate cancer include serum prostate specific antigen (PSA) examination, transrectal ultrasound (TRUS), computer tomography (CT) image examination, magnetic resonance (MR) image inspection, biopsy inspection, etc [6]. This paper proposes a new method of prostate segmentation based on MR images, denoted as ProSegNet. ProSegNet can automatically segment the prostate from the MR image and accurately determine the position, boundary, and volume of the prostate, so as to help clinicians quickly locate the prostate, identify abnormal shapes, and calculate the PSA concentration based on the volume. (4) To obtain more accurate segmentation results, we add a prostate contour segmentation branch to the output of the segmentation network to learn the contour features of the prostate and further refine the segmentation results

RELATED WORK
TRUNCATED INTENSITY STRETCHING IMAGE ENHANCEMENT
ProSegNet
MULTI-TASK JOINT TRAINING
EXPERIMENTAL RESULTS AND DISCUSSION
EVALUATION CRITERIA
CONCLUSION
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