Propranolol response in patients with segmental versus focal facial hemangiomas: A retrospective case-control study

Abstract

To the Editor: About 10% of infantile hemangiomas (IHs) are located on the face. They can be subdivided into focal facial hemangiomas (FFHs) and segmental facial hemangiomas (SFHs). SFHs are confined to anatomically defined segments and are frequently associated with cerebrovascular and other anomalies1; patients with definite or possible PHACE (posterior fossa malformations, hemangiomas, arterial anomalies, cardiac defects, eye abnormalities) syndrome have SFH diameters >5 cm.2 Because their proliferative phase is longer, SFHs frequently require extended periods of treatment.