Abstract
Objectives: The morbidity and mortality rate of peptic ulcer disease (PUD) is quite high. For example proportion of PUD in China was 17.2%. There is a lack of epidemiological data available for this disease in Indonesia. This study aims to determine the proportion of PUD in Haji Hospital Jakarta and to describe the risk factors of age, sex, and patient history of NSAIDs medication.Materials and Methods: This was a cross sectional study. Samples were patients who undergo esophagogastroduodenoscopy (EGD) examinations at the Hajj Hospital Jakarta from 2015 until 2018. Samples who met the inclusion dan exclusion criteria were selected randomly as needed. Data of chief complaints, diagnosis, age, sex, and history of NSAIDs medication were taken from the medical record.Result and Discussions: 112 samples were selected in this study. Major chief complaint was dyspepsia (42.9%). The proportion of PUD was 16 (14.3%) and predominantly male (75%). Most of the samples with PUD were >46 years old (68.8%). History of NSAIDs medications were 81.3% and most commonly used was mefenamic acid (41.2%). There was no significant association between PUD with sex (p>0.005), but there was a significant association between PUD and age (p < 0.005). Furthermore, older people more than 46 years were 11.5 times more likely to develop peptic ulceration than below 46 years (PR= 11.556).Conclusion: Elderly people should be more aware of the risk of getting PUD, especially those who had a history of NSAIDs medication.International Journal of Human and Health Sciences Vol. 05 No. 01 January’21 Page: 27-30
Highlights
Peptic ulcer disease (PUD) is defined as breaks into submucosal depth or inner lining of the stomach and/or duodenum more than 5 mm
Dyspepsia has a close relationship with PUD, whereas in previous studies half of patients with dyspepsia were subjected to EGD examination, subsequently it was found that those patients were indicated to have inflammation in the mucosa and submucosa gaster or duodenum.[2]
Many studies showed that the effect of long-term use of NSAIDs is a major cause of peptic ulcer infections other than H. pylori
Summary
Peptic ulcer disease (PUD) is defined as breaks into submucosal depth or inner lining of the stomach and/or duodenum more than 5 mm. 1. Department of Internal Medicine Faculty of Medicine Universitas Islam Negeri Syarif Hidayatullah Jakarta, Indonesia 2. Department of Clinical Nutrition Faculty of Medicine Universitas Islam Negeri Syarif Hidayatullah Jakarta, Indonesia
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