Abstract
Propafenone Overdose-induced Arrhythmia and Subsequent Correction After Administration of Sodium Bicarbonate
Highlights
Empty Line Calibri Size 12 History of present illness: 71-year old woman presented to the emergency department with near-syncope, chest pain, and shortness of breath
There are several potential causes for these ECG findings, but put together with the patient’s history, we were suspicious of sodium channel blockers being the most likely cause
Propafenone is a class 1C anti-arrhythmic that slows influx of sodium ions into the cells. It slows the rate of increase of the action potential thereby prolonging conduction and refractoriness in all areas of the myocardium.[1]
Summary
Propafenone Overdose-induced Arrhythmia and Subsequent Correction After Administration of Sodium Bicarbonate Patrick Bruss, MD* and Peter Fuller, MD^ *The Toledo Hospital, Emergency Physicians of Northwest Ohio, Toledo, OH ^University of Toledo Medical College, Department of Emergency Medicine, Toledo, OH
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