Abstract
BackgroundMany countries are grappling with growing numbers of parents who delay or refuse recommended vaccinations for their children. This has created a need for strategies to address vaccine hesitancy (VH) and better support parental decision-making regarding vaccination.AimTo assess vaccination intention (VI) and VH among parents who received an individual motivational-interview (MI) based intervention on infant immunisation during post-partum stay at a maternity ward between March 2014 and February 2015.MethodsThis non-controlled pre-/post-intervention study was conducted using the results from parents enrolled in the intervention arm of the PromoVaQ randomised control trial (RCT), which was conducted in four maternity wards across the Province of Quebec. Participants (n = 1,223) completed pre- and post-intervention questionnaires on VI and VH using Opel’s score. Pre-/post-intervention measures were compared using McNemar’s test for categorical variables and Wilcoxon signed-rank test for continuous variables.ResultsPre-intervention: overall VI was 78% and significantly differed across maternity wards (74%, 77%, 84%, 79%, p = 0.02). Post-intervention: VI rose significantly across maternity wards (89%, 85%, 95%, 93%) and the overall increase in VI was 12% (78% vs 90%, p < 0.0001). VH corroborated these observations, pre- vs post-intervention, for each maternity ward (28% vs 16%, 29% vs 21%, 27% vs 17%, 24% vs 13%). Overall, VH was curbed post-intervention by 40% (27% vs 16%; p < 0.0001).ConclusionsCompared with pre-intervention status, participants who received the MI-based intervention on immunisation displayed lower hesitancy and greater intention to vaccinate their infant at 2 months of age.
Highlights
According to data from the World Health Organization (WHO), 19.5 million children worldwide failed to receive routine life-saving vaccinations in 2016 while ca 90,000 children died from measles, a vaccine-preventable disease [1]
To assess the post-intervention impact on vaccination intention (VI) and vaccine hesitancy (VH), we designed a nested non-controlled pre-/post-intervention study using data from consenting parents enrolled in the intervention arm of a pragmatic, unblinded, parallel-randomised controlled trial (RCT) (NCT02666872); this study design is recognised as being suitable to determine the impact of an experimental intervention in a single arm study [16]
The RCT was conducted in four university hospital maternity wards of the Province of Quebec, collectively accounting for over 20% of all births province wide
Summary
According to data from the World Health Organization (WHO), 19.5 million children worldwide failed to receive routine life-saving vaccinations in 2016 while ca 90,000 children died from measles, a vaccine-preventable disease [1]. Randomised in intervention arm but did not receive the intervention (refusal to participate, earlier than expected hospital discharge, or a health condition in the mother or her newborn): 58. Aim: To assess vaccination intention (VI) and VH among parents who received an individual motivational-interview (MI) based intervention on infant immunisation during post-partum stay at a maternity ward between March 2014 and February 2015. Methods: This non-controlled pre-/postintervention study was conducted using the results from parents enrolled in the intervention arm of the PromoVaQ randomised control trial (RCT), which was conducted in four maternity wards across the Province of Quebec. Conclusions: Compared with pre-intervention status, participants who received the MI-based intervention on immunisation displayed lower hesitancy and greater intention to vaccinate their infant at 2 months of age
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