Promising nanocompounds based on carbon and ultrafine metal particles with antibacterial properties in the development of a new generation of nano-disinfectants

Abstract

Using the unique properties of nanomaterials leads to new and original solutions to the problems that are currently emerging, for example, to solving the problem of the development of various infections caused by bacterial strains that are resistant to traditional antibacterial drugs. This fully applies to bacterial strains—pathogens of animal and human infections with resistance to drugs—as well as to bacteria on the surfaces in laboratories and hospitals that acquired new resistance to a wide range of chemicals and compounds that were previously used against them. In this regard, the development of a new generation of nano-disinfectants based on fundamentally different active components, in particular, on the basis of carbon nano compounds and ultrafine metal particles, is of particular interest. Evaluation of such nanoscale compounds and/or particles was carried out using a recombinant strain of Escherichia coli K12 TG1 with the cloned luxCDABE genes of Vibrio fischeri by bioluminescent analysis. The compounds of nanocarbon and metal nanoparticles that can be used as an active principle in the creation of antibacterial drugs used in medicine and veterinary medicine are defined.