Abstract
USING thoracic duct lymph drainage, Cronemiller and his associates1were able to reduce the blood urea nitrogen (BUN) level and remove edema in patients with uremia due to advanced chronic renal insufficiency. On the other hand, Dumont and Mulholland2indicated that thoracic duct drainage was effective in reducing ascites in patients with liver cirrhosis. In the field of organ transplantation, removal of lymphocytes from the body has drawn particular attention because lymphocytes are significantly involved in antibody production. Lymphocytes can be eliminated from the body of animals in any one of the following three ways: (1) the use of antilymphocytic immune serum3-6; (2) selective irradiation by a β-emitting isotope7-10; and (3) thoracic duct lymph drainage.11,13McGregor and Gowans11demonstrated that chronic thoracic duct lymph drainage can reduce the rat's lymphocytes in the peripheral blood, inhibit antibody production, and prolong skin homograft survival time. Samuelson
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