Abstract
Background The coronary slow flow phenomenon (CSFP) is an atherosclerotic process that causes ischemia at the microvascular level. The CSFP may affect P wave durations, especially P wave peak time (PWPT), by microvascular ischemia, left ventricular diastolic dysfunction, and changes in the left atrial dimension. Therefore, in the present study, we aimed to assess PWPT in the CSFP. Method One hundred and ninety-five patients were included in this single-center, retrospective study. Ninety patients were enrolled in the CSFP group and 105 patients in the control group. PWPT was defined as the duration between the beginning and peak of the p wave and obtained from the leads Dıı and Vı. Results The mean age of the study population was 48.5 ± 9.5, and 108 (55.3%) of the patients were female. We found PWPT was longer in the CSFP group than in the control group. Correlation analysis showed a positive correlation between PWPT in both leads (DII, Vı) and left atrial anterior-posterior diameter, mean TIMI frame count (TFC), and E/e. A significant relationship was observed between mean TFC, E/e, EF, heart rate, and PWPT in lead Dıı (β coefficient = 0.33, 95% CI 0.44–1.33, p < 0.001, β coefficient = 0.23, 95% CI 0.25–1.85, p=0.01, β coefficient = -0.140, 95% CI −1.04–−0.53, p=0.03, and β coefficient = −0.13, 95% CI −0.29–−0.014, p=0.03, respectively) in multivariable linear analysis. Conclusion In the present study, we found prolonged PWPT in patients with the CSFP and found a relationship between PWPT and mean TFC.
Highlights
Background. e coronary slow flow phenomenon (CSFP) is an atherosclerotic process that causes ischemia at the microvascular level. e CSFP may affect P wave durations, especially P wave peak time (PWPT), by microvascular ischemia, left ventricular diastolic dysfunction, and changes in the left atrial dimension. erefore, in the present study, we aimed to assess PWPT in the CSFP
Many P wave parameters have been obtained from the ECG, such as P wave dispersion (PWdıs), maximum P wave duration (PWDmax), and P wave terminal force from lead VI (PWTF). ey have been used for the assessment of LV diastolic dysfunction (LVDD) and left atrial (LA) dilatation in studies [11, 12]. e correlation of left ventricular end-diastolic pressure (LVEDP) with PWPT has been shown in previous studies [13, 14]
One hundred and ninety-five patients were included in the present study. e study consisted of two groups as the CSFP (n 90) and normal coronary flow (NCF) (n 105). e mean age of the patients was 48.5 ± 9.5, and 108 (55.3%) of the patients were female. ere was no statistical difference between the two groups in terms of the medications
Summary
Background. e coronary slow flow phenomenon (CSFP) is an atherosclerotic process that causes ischemia at the microvascular level. e CSFP may affect P wave durations, especially P wave peak time (PWPT), by microvascular ischemia, left ventricular diastolic dysfunction, and changes in the left atrial dimension. erefore, in the present study, we aimed to assess PWPT in the CSFP. E coronary slow flow phenomenon (CSFP) is an atherosclerotic process that causes ischemia at the microvascular level. E CSFP may affect P wave durations, especially P wave peak time (PWPT), by microvascular ischemia, left ventricular diastolic dysfunction, and changes in the left atrial dimension. Previous studies have shown that the CSFP is an atherosclerotic process that causes ischemia at the microvascular level [4, 5]. LV diastolic dysfunction (LVDD) and changes in LA volume in patients with the CSFP have been shown in previous studies [7,8,9,10]. We considered the CSFP may affect P wave durations, especially PWTF and PWPT, by doing microvascular ischemia, LVDD, and changes in LA dimension. We considered the CSFP may affect P wave durations, especially PWTF and PWPT, by doing microvascular ischemia, LVDD, and changes in LA dimension. erefore, this study aims to assess PWPT in patients with the CSFP
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