Prolonged Collagen Peptide Supplementation and Resistance Exercise Training Affects Body Composition in Recreationally Active Men.

Marius Kirmse,Wilhelm Bloch,Vanessa Oertzen-Hagemann,Petra Platen,Markus De Marées

doi:10.3390/nu11051154

Marius Kirmse, Wilhelm Bloch + Show 3 more

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https://doi.org/10.3390/nu11051154

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Journal: Nutrients	Publication Date: May 23, 2019
Citations: 34	License type: CC BY 4.0

Affiliation: Ruhr University Bochum, German Sport University Cologne

Abstract

We aimed to determine the effects of long-term collagen peptide (CP) supplementation and resistance exercise training (RET) on body composition, strength, and muscle fiber cross-sectional area (fCSA) in recreationally active men. Fifty-seven young men were randomly and double-blinded divided into a group receiving either collagen peptides (COL, 15 g/day) or a placebo (PLA). Strength testing, bioimpedance analysis, and muscle biopsies were used prior to and after an RET intervention. Food record protocols were performed during the RET intervention. The groups trained three times a week for 12 weeks. Baseline parameters showed no differences between groups, and the external training load and dietary food intake were also similar. COL showed a significant increase in fat-free mass (FFM) compared with the placebo group (p < 0.05). Body fat mass (BFM) was unchanged in COL, whereas a significant increase in BFM was observed in PLA. Both groups showed significant increases in all strength tests, with a trend for a slightly more pronounced effect in COL. The fCSA of type II muscle fibers increased significantly in both groups without differences between the two groups. We firstly demonstrated improved body composition in healthy, recreationally active men subsequent to prolonged CP supplementation in combination with RET. As the observed increase in FFM was not reflected in differences in fCSA hypertrophy between groups, we assume enhanced passive connective tissue adaptations in COL due to CP intake.

Highlights

The effects of additional protein intake are widely known to augment muscle protein biosynthesis (MPS) [1], promote higher muscle fiber cross-sectional area and strength enhancement [2,3], and benefit body composition by increasing fat-free mass (FFM) and decreasing body fat mass (BFM) [2]
The main result of this investigation is that a significant increase in FFM was observed for COL compared with PLA, with no differences in fiber cross-sectional area (fCSA) hypertrophy between groups
As already shown in older sarcopenic men and premenopausal women, we measured a significant increase in FFM in COL compared with PLA

Summary

Introduction

The use of various protein supplements in combination with exercise regimens, such as resistance exercise training (RET), is well established in elite athletes as well as in recreationally active individuals.The effects of additional protein intake are widely known to augment muscle protein biosynthesis (MPS) [1], promote higher muscle fiber cross-sectional area (fCSA) and strength enhancement [2,3], and benefit body composition by increasing fat-free mass (FFM) and decreasing body fat mass (BFM) [2].postexercise recovery can be positively affected by different protein intake strategies, implying that additional protein facilitates muscle repair, immune function, and muscle remodeling [4].These effects have been predominately described for essential/branched-chained amino acids such as leucine, which is associated with improved muscle cell metabolism as a result of triggering the mammalian target of rapamycin (mTOR) pathway [5].Nutrients 2019, 11, 1154; doi:10.3390/nu11051154 www.mdpi.com/journal/nutrientsBesides contractile muscle fiber adaptations, passive tissue components are able to adapt to mechanical loads [6,7,8]. Postexercise recovery can be positively affected by different protein intake strategies, implying that additional protein facilitates muscle repair, immune function, and muscle remodeling [4] These effects have been predominately described for essential/branched-chained amino acids such as leucine, which is associated with improved muscle cell metabolism as a result of triggering the mammalian target of rapamycin (mTOR) pathway [5]. The regulatory mechanisms of passive tissue protein biosynthesis, triggered by stretching the tissue or muscular activity, were well described by Kjær [10], but are only partly understood. It is unclear whether a specific protein supplementation is able to enhance the adaption of the mentioned passive tissue components. The primary structural protein of connective tissues is collagen [4]

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