Proliferative vitreoretinopathy secondary to degenerative retinoschisis: A case series

Safia Ahmed,Gupta M,Sohail Ahmed,Carpi Olali,Mansvkhlal Amer

doi:10.5348/ijcri-201454-cs-10040

Abstract

Introduction: We report two cases proliferative vitreoretinopathy that occurred as complication of degenerative retinoschisis. Case Series: Two patients; a male and a female with vitreo-retinal hemorrhage seen in our clinic were evaluated and retinoschisis found as the only cause of the bleeding. Both were treated with Argon barrier photocoagulation which arrested the hemorrhage and resolved the visual symptoms. Conclusion: It has been suggested that retinal ischemia occurs in retinoschisis and this triggers upregulation of growth factors and subsequent formation of new vessels. This hypothesis would need to be tested to ascertain the particular growth factors, that trigger this process and if other cytokines and interleukins also play a role as the process is a vitreoretinpathy.

Highlights

We report two cases proliferative vitreoretinopathy that occurred as complication of degenerative retinoschisis
It has been suggested that retinal ischemia occurs in retinoschisis and this triggers upregulation of growth factors and subsequent formation of new vessels
We present two cases of retinoschisis who had ocular symptoms related to vitreous hemorrhage which occurred as a complication of the retinoschisis only and the treatment we instituted to arrest this complication

Summary

INTRODUCTION

Degenerative retinoschisis rarely present with symptoms because of their peripheral location [1]. Case 1: A 58-year-old male presented with a week history of triangle-like floater in his right eye His vision was otherwise normal and there was no medical history of significance. A few months later, repeat retinal angiograms showed areas of non-perfusion in and around the retinoschisis with hyperflourescence of the new vessels He had barrier argon laser photocoagulation and has since remained stable with normal vision and no vitreous hemorrhage. Case 2: A 60 year old female patient was referred because of bleeding in the lower mid-peripheral retina of the left eye noticed by an optician during routine visit. She had had no ocular problems but was on treatment for hypertension. Vitreous hemorrhage in the last 18 months after the laser treatment

Findings

DISCUSSION

CONCLUSION