Abstract
In 1906, it was confirmed that the pertussis was caused by Bordetella pertussis (BP). Virulence factors of BP had been studied widely for over a hundred years, however, the pertussis pathology remains largely unknown.The development of a baboon model will promote the study of the pathogenesis of BP infection and disease, and the understanding about the pathogenesis is helpful for the prevention and therapeutics of pertussis. Key words: Pertussis; Virulence factors; Pathogenesis; Immune suppression
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