Abstract

Invasion and metastasis are the important biological features of malignant neoplasms,and are the main reasons for the death of patients with pancreatic neoplasms.Current researches find that invasion and metastasis of pancreatic neoplasms are closely related to series of molecular biological changes,including' abnormalities of tumor metastasis-related genes,degradation of extracellular matrix,tumor-induced angiogenesis,changes of the adhesion molecules and cytokines.However,the definite mechanism still remains unclear,and further researches are needed. Key words: Pancreatic neoplasms; Gene; Matrix metalloproteinases; Cell adhesion molecule; Cyto

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