Abstract

Rotavirus is the most important pathogen causing severe diarrhea in infants and young children worldwide, and for rotavirus diarrhea there is no specific treatment so far.At present, there are a variety of claims on the pathogenesis of rotavirus infection, but none is conclusive.In the process of infection, rotavirus pathogens must overcome antiviral innate immune response that can replicate in host cell.Rotavirus encoded proteins play an important role in the process of rotavirus infection.This paper reviews the role of rotavirus encoding proteins in the pathogenesis of rotavirus infection. Key words: Rotavirus; Innate immunity; Structural protein; Nonstructural protein

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