Progress of the Comparative MHC Committee and a summary of the Comparative MHC Workshops held at the 32nd ISAG, Edinburgh and the 9th IVIS, Tokyo, 2010

Abstract

The comparative MHC Nomenclature Committee was formed following a recommendation by the International Society for Animal Genetics (ISAG) at its meeting in Göttingen, Germany in 2002. The committee subsequently became affiliated to VIC, the Veterinary Immunology Committee of IUIS; the International Union of Immunological Societies, which is the umbrella organization for immunology societies worldwide. The committee currently fulfils three roles: (1) to establish guidelines for MHC nomenclature in species outside of human and mouse, (2) to facilitate the development of databases which provide a source of validated MHC sequences with official nomenclatures for associated species (immuno-polymorphism database IPD-MHC) and (3) to facilitate scientific discussion on comparative aspects of MHC biology. The committee currently comprises individuals representing a range of species nomenclature committees. This report summarises progress the committee has made in addressing its core objectives as well as the principal outputs from the Comparative MHC Workshops held at the 32nd International Society for Animal Genetics (ISAG) conference in Edinburgh, UK in July 2010 as well as in August 2010 at the 9th International Veterinary Immunology Symposium (IVIS) in Tokyo, Japan. Additional data from posters and presentations at related workshops focussing on aspects of MHC biology are also included where appropriate.