Abstract
Diabetic kidney disease (DKD) is a one of the common complications of diabetes, and is a leading cause of end-stage renal disease. Early diagnosis and disease course prediction of DKD become crucial for clinical management improvement due to the lack of effective treatment. Although proteinuria and serum creatinine are important indicators for early diagnosis and prognosis evaluation of DKD, in fact, their diagnostic efficiency is very limited. Therefore, there is an urgent need to find more efficient biomarkers in diagnosing or predicting DKD. This article reviewed recent advances in the study of biomarkers of DKD so as to provide ideas for the development of diagnostic strategies. Key words: Diabetic kidney disease; Biomarkers; Early diagnosis; Prognosis evaluation
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