Abstract
Targeted drug delivery system is an effective method for the diagnosis and treatment of cancer, it has received much attention because of its low side effects and therapeutic efficacy. Folic acid receptor is highly expressed on the surface of most cancer cells, but is low or not expressed on the surface of normal cells, and the ligand folate has a high affinity. Folic acid receptor is attached to drug carriers and can be targeted to cancer cells. This paper introduces folic acid and folate receptors, briefly describes the mechanism of action of folic acid receptor-mediated targeted drug delivery, discusses the progress on four types of folic acid-folate receptor-mediated cancer treatment: folate acid-conjugated magnetic nanoparticles, drug binding of small-molecule folic acid, folic acid receptor-bound protein, and folic acid-conjugated polysialic acid. It also analyzes the favorable points and future development trends of each treatment mechanism.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
