Abstract

Neoadjuvant chemotherapy (NAC) has been widely used in Ⅱ A, Ⅱ B, Ⅲ A stage and locally advanced breast cancer. The best way to evaluate NAC effect is to detect the changes in total tumor lesion volume by three-dimensional reconstruction under magnetic resonance imaging (MRI). At present, it is a hotspot for many scholars to effectively evaluate the efficacy of NAC and the impact of shrinkage modes on the evaluation after NAC in breast cancer by combination of multiple parameters, such as the area under receiver operating characteristic curve (ROC), time-intensity curve (TIC) type and minimum apparent diffusion coefficient (ADC). To provide more practical and accurate means and methods in evaluating the effect of NAC in breast cancer for clinic is the medical researchers' eternal target. Key words: Breast neoplasms; Neoadjuvant chemotherapy; Magnetic resonance imaging

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