Abstract
Innate immunity system is the first line of defense against microbial invasion. It recognizes and re-moves pathogenic microorganisms through the host pattern recognition receptors (PRRs). Toll-like receptors (TLRs) and Nod-like receptors (NLRs) can mediate immune recognition. Since the two important receptors not only initiate the innate immune responses but also stimulate the adaptive immunity responses through pathogen-associated molecular patterns (PAMPa), they are linking the innate and adaptive immunity. Poly-morphonuclear neutrophils (PMNs) are the most important inflammatory cells in the early inflammation. TLRs play a crucial role in the processes of adhesion, activation and apoptosis of PMNs so as to maintain the stability of the internal environment. Key words: Toll-like receptors; Nod-like receptors; Polymorphonuclear neutrophils
Published Version
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