Abstract
Along with the development of modern science and technology, the clinical application of deafness gene detection technology is becoming more and more extensive. Gene detection technology has experienced the process from the gene chip technology to the first generation DNA sequencing technology, and then to the second generation DNA sequencing technology. They are widely used in diagnosis of hereditary deafness etiology in clinical practice. In recent years, they are further applicated in the detection of neonatal deafness gene screening, prenatal diagnosis and pre marital and pre pregnancy. This paper will reviews the significance, technology progress, clinical diagnosis and application of gene detection technology.
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