Progress in Synthetic Trends Followed for the Development of 1,2,3-Triazole Derivatives: A Review

Abstract

Since the beginning of click chemistry, 1,2,3-triazoles has been at the center of modern organic chemistry. This versatile framework has found broad applications in organic synthesis, drug discovery, chemical biology, polymer chemistry, supramolecular chemistry, bioconjugation, fluorescent imaging, and materials sciences. Due to tremendous use of 1,2,3-triazoles in chemistry, synthesis of this moiety from the easily available chemicals is desirable. This review covers different conventional and non-conventional approaches adopted for the synthesis of 1,2,3-triazole derivatives.