Progress in Regional Cancer Therapy

Abstract

Advances in Drug Delivery.- Advances in Drug Delivery to Cancer Patients: Introduction.- Technical Developments in the Delivery of Antineoplastic Agents.- Is There a Pharmacologic Rationale for Continuous Cancer Chemotherapy?.- Central Venous Access in Children Through a Fully Implantable Drug Delivery System.- Intraportal Chemotherapy for Colorectal Hepatic Metastases.- Liver Metastases.- Prophylactic and Adjuvant Regional Chemotherapy of the Liver in Colorectal Malignancies.- Randomized Multicenter Trial on Adjuvant Intraportal Chemotherapy for Colorectal Cancer (SAKK 40/81).- Enhancement of Cytotoxic Efficacy of 5-Deoxy-5-fluorouridine in Acetoxymethyl-methylnitrosamine-Induced Colorectal Adenocarcinomas in SD Rats by Locoregional Administration into the Inferior Mesenteric Artery.- Second Hepatic Resections in Patients with Liver Metastases from Colorectal Carcinoma.- Six Years of Experience with Local Chemotherapy of the Liver.- Regional Therapy of Hepatic Metastases: Prognostic Factors.- Regional Therapy with 5-Fluorouracil: Dependence of Systemic Concentrations on the Infusion Rate.- Combined Regional and Systemic Chemotherapy in Hepatic Metastases of Colorectal Carcinoma: Continuous IA Vs Simultaneous IA/IV FUDR Infusion.- Intra-arterial Chemotherapy of Liver Metastases.- Current Standards and Limits in Treatment of Hepatic Metastases.- Degradable Starch Microspheres in Intra-arterial Tumor Treatment: An Overview.- Increasing the Uptake of a Low Molecular Weight Marker in Liver Tumours by Degradable Starch Microspheres: Possible Mechanisms of Action.- Dextrane Particle Use in Regional Chemotherapy: Problems of Monitoring.- Chemoembolization of Hepatic Tumors with Degradable Starch Microspheres.- Head and Neck Tumors.- Cytostatic Treatment of Advanced Squamous Cell Carcinoma of the Maxillofacial Region.- A Complex Chemotherapeutic Concept in the Treatment of Oral Carcinomas with Cisplatin and 5-Fluorouracil.- Pathological Assessment of the Results of Intra-arterial Chemotherapy for Head and Neck Carcinomas by Serial Sections of the Whole Specimen.- The Bypass Method in Head and Neck Cancer.- Intratumoral Treatment of Incurable Head and Neck Cancer with Recombinant Human Tumor Necrosis Factor-?.- Preoperative Local Immunotherapy with OK-432 (Picibanil) in Patients with Squamous Cell Cancer of the Oral Cavity.- Extremity Tumors.- Intra-arterial Chemotherapy, Preoperative and Postoperative Radiotherapy, and Surgery for Primary Unresectable High-Grade Soft Tissue Sarcomas of the Extremities.- Regional Induction Chemotherapy Followed by Radiotherapy and/or Surgery in Management of Large and Aggressive Sarcomas in Shoulder, Pelvis and Limbs.- Neo-adjuvant Chemotherapy for Osteosarcoma of the Extremities: The Experience at the Rizzoli Institute in 210 Patients Treated with Two Successively Activated Preoperative Protocols Using High-Dose or Moderate-Dose Methotrexate + Cisplatin or High-Dose Methotrexate + Cisplatin + Doxorubicin.- Neo-adjuvant Therapy of Soft Tissue Sarcomas of the Extremities with Intra-arterial Chemotherapy and Radiation.- Melanoma.- Isolation Perfusion for Malignant Melanomas: Established Facts and Parameters to Be Clarified.- Regional Extremity Perfusion in Patients with Malignant Melanoma.- Preliminary Results of a Double Perfusion Schedule with Melphalan in Measurable Melanoma.- Melphalan in Isolated Limb Perfusion for Malignant Melanoma, Bolus for Divided Dose, Tissue Levels, the pH Effect.- Isolation Perfusion of Malignant Soft Tissue Tumors.- Intravesical Therapy.- The Effect of Topical Adriamycin in Superficial Bladder Tumors: A 5-Year Follow-up.- Topical Instillation of Mitomycin C in the Treatment of Superficial Bladder Tumors: Long-Term Observation.- Mitomycin and Hyaluronidase in the Prevention of Recurrent Bladder Tumor.- How Effective is Topical Interferon-?2b for Preventing Recurrence of Superficial Bladder Cancer.- Neo-adjuvant Intra-arterial Chemotherapy for Treatment of Locally Advanced Bladder Cancer: Therapeutic Protocol and Preliminary Report.- Radiotherapy.- Reconstructive Microsurgery and Radiotherapy in Advanced Tumors of the Head and Neck.- Palliation of Nonresectable Esophageal Cancer by Irridium-192 Intraluminal Afterloading.- Interstitial Radiotherapy with Iridium-192 in the Treatment of Early Breast Cancer.- Intracavitary High-Dose-Rate Afterloading Irradiation in the Treatment of Cancer of the Esophagus and Gastroesophageal Junction.- External Radiotherapy for Local and Regional Control of Lung Cancer.- Hyperthermia.- Clinical Experience with a Multifrequency Hyperthermia System and Chemotherapy in the Treatment of Superficial Metastases.- Recent Clinical Experience with an Annular Phased Array Hyperthermia System in the Treatment of Advanced Recurrences in the Pelvis.- The Viennese Interstitial System KHS 9/W 18: Homogenous Hyperthermia with Simultaneous Radiation in Deep-seated Tumors with Integrated Heat Protection of Normal Tissue.- Thermoradiotherapy of Superficial and Half-Deep-seated Tumors: Thermal Profiles and Tumor Response.- Comparison of Leakage Measurement Using 99mTc-Labeled Red Blood Cells and Peripheral Melphalan Determination in Hyperthermic Isolation Perfusion of the Extremities.- Clinical and Histopathological Aspects of Hyperthermic Isolated Regional Perfusion of Soft Tissue Sarcomas of the Extremities.- Laser Therapy.- Experimental Basis of CO2 Laser Application in Tumor Surgery.- Experience with CO2 Laser in Tumor Surgery.- Nd: YAG Laser Application in the Surgical Treatment of Cancer.- Neodymium: YAG Laser Therapy in Gastroduodenal Cancer.- Innovative Approaches.- The Use of Tumor-Infiltrating Lymphocytes in Cancer Therapy.- Adoptive Immunotherapy for Renal Adenocarcinoma: Use of Oxidizing Mitogen-Treated Mononuclear Leukocytes and Continuous Infusion of Interleukin-2.- Processing of Antigen-Antibody Complexes at the Level of the Tumor Cell.- Regional Immunotherapy and Chemotherapy in Lung Cancer.