Abstract
Norovirus is one of the leading causes of acute non-bacterial gastroenteritis. Emergence of new genotypes due to frequent genetic recombination and antigenic drift increases the prevalence of norovirus infection worldwide. Norovirus infection has become a global public health concern. This review focused on disease burden, vaccine research, cell culture and animal models regarding norovirus infection. Key words: Norovirus; Gastroenteritis; Vaccine
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