Abstract
Innate lymphoid cells are the most recently discovered family of lymphocytes and a group of innate immune cells. They cannot directly participate in specific immune responses due to lack of pattern recognition and recombination receptors. According to the transcription factors that regulate their development and function and the cytokines that they can produce, ILCs can be divided into three groups: ILC1, ILC2 and ILC3. ILC1 and ILC3 also include several different subtypes. ILCs play an important role in maintaining the integrity of intestinal mucosal epithelium, regulating intestinal microbiote, promoting the development of the intestinal immune system and regulating intestinal inflammation. This article reviews the roles of ILCs in intestinal homeostasis maintenance and the development of intestinal diseases. Key words: Innate lymphoid cell; Intestinal microbiote; Inflammatory bowel disease; Colorectal cancer
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