Abstract
The induced pluripotent stem cells(iPS cells) were regarded as a milestone of life sciences,which originated a relatively easy-to-use and more stable somatic cell nuclear reprogramming method, having apotential value in basic research of biology and clinical application. However, its applications were limited by high carcinogenic rate and low efficiency of reprogramming. Currently, iPS cell technology is being continuously improved. This article reviewed the history and the latest research progress in iPS cells. Key words: Induced pluripotent stem cell; Reprogramming; Stem cell factor; Gene transfection
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