Abstract
Objective. To assess the discriminatory ability of the PELOD 2 and pSOFA scales in the conditions of multidisciplinary neonatal intensive care unit. Material and methods . It is a prospective, observational, single-center study. The end points are to assess the severity of the condition on the PELOD 2 and pSOFA scales; 28-day survival. The study includes 121 patients. Results. While studying the discriminating power of the scales we have found that all scales have good model quality. At the same time, the pSOFA evaluation system has a statistically more significant (p<0.05) area under the ROC curve (0.903±0.09). Our analysis has not found significant differences in the characteristics of surrogate endpoints between the compared scales in the conditions of comparable points of separation of death risks (p<0.05). Conclusion. The high discrimination ability of the pSOFA scale allows us to recommend it for clinical use in neonatal intensive care units.
Highlights
While studying the discriminating power of the scales we have found that all scales have good model quality
The high discrimination ability of the pSOFA scale allows us to recommend it for clinical use in neonatal intensive care units
Conflict of interest: The authors of this article confirmed the lack of conflict of interest and financial support, which should be reported
Summary
Оценка дискриминационной способности шкал PELOD 2 и pSOFA в условиях многопрофильного неонатального отделения интенсивной терапии. Конечные точки – оценка тяжести состояния по шкалам PELOD 2 и pSOFA; 28-дневная выживаемость. Исследование дискриминационной мощности шкал показало, что все они имеют хорошее качество модели. В то же время оценочная система pSOFA обладает статистически значимо большей (p
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