Abstract
Proadrenomedulin (proADM) is a novel prognostic biomarker employed in pneumonia and more recently in severe sepsis and septic shock. Release kinetics of proADM in this disease has not been studied. in this research we analyze the variation in plasma levels of this prohormone based upon the type of causative agent, the site of infection and the presence of renal failure.
Highlights
Prognostic value of proadrenomedulin in severe sepsis and septic shock is independent of etiology and focus of infection
Proadrenomedulin is a novel prognostic biomarker employed in pneumonia and more recently in severe sepsis and septic shock
Statistical analysis: c2 test for categorical variables; comparison of proADM levels based upon etiologic agent, site of infection and presence of renal failure were performed by using repeated measures analysis of variance (ANOVA)
Summary
Proadrenomedulin (proADM) is a novel prognostic biomarker employed in pneumonia and more recently in severe sepsis and septic shock. In this research we analyze the variation in plasma levels of this prohormone based upon the type of causative agent, the site of infection and the presence of renal failure
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