Abstract
目的： 探讨C反应蛋白（CRP）在弥漫性大B细胞淋巴瘤（DLBCL）中的表达及其预后预测价值。 方法： 收集复旦大学附属中山医院2011—2018年治疗前活检或手术切除的DLBCL病例，制作组织芯片，运用免疫组织化学方法检测CRP在DLBCL中的表达情况。χ²检验和Kaplan-Meier分析进行临床病理特征和总生存期的相关性评估。 结果： 共纳入198例治疗前DLBCL病例。男性111例，女性87例（男女比为1.3∶1.0）。中位年龄60岁。免疫组织化学检测示20例DLBCL肿瘤组织CRP阳性（10.1%）。与B症状及国际预后指数（IPI）具有显著相关性。单因素分析显示CRP阳性患者具有较差预后（P=0.040）。 结论： CRP在DLBCL中具有一定比例的表达，CRP阳性提示预后不良。.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Zhonghua bing li xue za zhi = Chinese journal of pathology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
