Prognostic significance of changes in the level physical capacity to assess the favorable dynamics of metabolic syndrome in patients with abdominal obesity

Abstract

Background . Abdominal obesity (AO) is a key factor of metabolic syndrome (MS) and risk factor of cardiovascular diseases (CVD). The level of physical capacity (PC) is an important diagnostic and prognostic criteria and a risk stratification factor in healthy individuals and patients with CVD. Objective . To evaluate the effect of changes in the level of PC on the course of MS in patients with AO on the background of non-drug correction of body weight. Design and methods . A 3-year prospective study was conducted on weight loss by non-drug methods in 153 patients with AO and MS and /or CVD risk factors. The dynamics of MS, indicators of carbohydrate and lipid metabolism, and blood pressure levels were evaluated depending on changes in the level of PC. Results . The favorable course of the MS was more common in patients with an increase in the level of PC than in patients with a decrease in this indicator (82.3 and 37.5 %, respectively; p = 0.0001). When increasing VO 2peak > the 5 % to 15 % chance of a favorable course of MS increases by 5.8 (1.5–22.3) and 15.1 (5.7–39.9) times, respectively. Conclusion . An increase in the level of PC is associated with a favorable MS dynamic.