Abstract
ObjectiveTo evaluate the prognostic performance of the neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR) for mortality in patients with acute stroke treated at a Peruvian hospital. DesignRetrospective cohort study. SettingTertiary care hospital. PatientsPatients aged ≥18 years with a diagnosis of acute stroke and admitted to the hospital from May 2019 to June 2021. InterventionsNone. Main variables of interestsNeutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and mortality. ResultsA total of 165 patients were included. The mean age was 66.1±14.2 years, and 59.4% were male. Only NLR had a performance superior to 0.7 (AUC: 0.75; 95%CI: 0.65–0.85), and its elevated levels were associated with an increased risk of mortality (aRR: 3.66; 95%CI: 1.77–8.85) after adjusting for confounders. ConclusionThe neutrophil-to-lymphocyte ratio has an acceptable prognostic performance for mortality in patients with acute stroke. Its use may be considered to stratify patients’ risk and to consider timely alternative care and management.
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